Pain Management
Resources
Basic InformationLatest News
Opioids Plus Other Drugs a Deadly Mix for Heavy UsersHealth Tip: Manage Pain With OpioidsDoctors More Cautious Now When Prescribing Opioids to KidsEven Wisdom Tooth Removal May Spur Opioid AddictionOnly a Quarter of Opioid Painkillers Taken After Most SurgeriesOpioid Use May Sometimes Trigger A-FibFDA Approves Powerful New Opioid Despite CriticismsNew Nerve Stimulation Technique Might Relieve Back PainDespite Opioid Crisis, Most Patients Want the Drugs for Post-Op PainFor Pain Relief, Why Not Try Drug-Free Alternatives?1 in 12 Americans Lives With Debilitating Chronic PainMindfulness May Be a Buffer Against PainCould a Placebo Pill Help Ease Your Back Pain?Chronic Pain May Drive Some to SuicideMonkey Trials Raise Hope for Non-Addictive Opioid AlternativeGovernment Rules Aimed at Curbing Opioid Prescriptions May Have BackfiredAs Opioid Epidemic Rages, Painkiller Prescriptions Don't DropMost Seniors Uninformed on Opioid UseSprained Ankle? Opioid Rx More Likely in Some States Than OthersOpioids Before Joint Replacement Tied to Worse RecoveryCould Botox Cousin Combat the Opioid Epidemic?Where Are Opioid Painkillers Prescribed the Most?Anti-seizure Meds Won't Ease Low Back PainMedical Marijuana a Hit With SeniorsRisky Prescribing Boosts Opioid Death RiskPatients on Opioids OK With Lower DosesPatterns of Potential Misuse Help Assess Risk of Opioid OverdoseHospitals Should, and Could, Avoid IV Opioids: StudyOpioid Makers' Perks to Docs Tied to More PrescriptionsPsychological Therapies May Help Older Adults With Chronic PainStudy Finds 31 Percent Use No Opioids After SurgeryAddictive Opioids Still Overprescribed After Surgery: StudyDoctors Curbing First-Time Prescriptions for OpioidsFDA Recalls Kratom Products Due to Salmonella ThreatMillions Get Wrong Treatment for Back Pain: StudyManaging Pain With Fewer Opioids After Joint ReplacementDoctors Present Recs For and Against Acupuncture for PainOpioids Don't Top Non-Opioids for Pain-Related FunctionOpioids Not Best Option for Back Pain, Arthritis, Study FindsGroup CBT, Pain Education Improve Pain, Physical FunctionChronic Opioid Users May Wish to Taper Opioid UseSome Pain Patients Can Cut Opioid Dose and Still Get ReliefAnother Downside to Opioid Use: Pneumonia?Long-Term Opioid Use Down Among U.S. Vets: StudyLosing Weight Eases Obesity-Related Pain. But How Much Is Enough?Do Over-the-Counter Painkillers Alter Emotions, Reasoning?Opioid Prescribing Trends in the VA Similar to Other SettingsHow to Avoid Opioid Addiction After SurgeryOpioids Aren't America's Only Painkiller ProblemWeight Loss Among Obese Tied to Improvements in Chronic Pain
Questions and AnswersVideosLinksBook Reviews
Related Topics

Depression: Depression & Related Conditions
Medical Disorders
Mental Disorders
Medications

Could Botox Cousin Combat the Opioid Epidemic?

HealthDay News
by -- Robert Preidt
Updated: Jul 20th 2018

new article illustration

FRIDAY, July 20, 2018 (HealthDay News) -- A modified type of botulinum toxin -- botox -- gave mice long-term pain relief and may someday be a safer alternative to opioids as a treatment for chronic pain, according to British researchers.

They "deconstructed" the botulinum molecule and reassembled it with an opioid called dermorphin. The resulting compound -- called Derm-BOT -- silenced pain signals from neurons in the spinal cords of mice.

But it isn't yet known whether the compound would produce the same results in people. Results of animal studies often aren't the same in humans.

"Injected into the spine, Derm-BOT relieves chronic pain -- such as that caused by nerve damage -- and avoids the adverse events of tolerance and addiction often associated with repeated opioid drug use," said study co-corresponding author Steve Hunt. He's a professor in the department of cell and developmental biology at University College London.

"It doesn't affect muscles like the botulinum toxin used to reduce wrinkles but it does block nerve pain for up to four months without affecting normal pain responses. It really could revolutionize how chronic pain is treated if we can translate it into clinic, removing the need for daily opioid intake," Hunt said in a university news release.

The study was published July 18 in the journal Science Translational Medicine.

The United States is in the throes of an opioid overdose epidemic. More than 2 million people are addicted to opioids, and most of them started with prescribed opioid painkillers. Opioid overdose is now a leading cause of death.

More information

The American Academy of Family Physicians has more on pain medicines.




Facebook

Amazon Smile

To quit smoking, call Connecticut QuitLine at 1-800-QUIT-NOW.

Children and Adult services are available now with no wait time.  Please contact HBH Intake Department at 860-548-0101, option 2.

 


powered by centersite dot net