Smoking
Resources
Basic InformationLatest News
Scientists Find Unsafe Levels of Known Carcinogen in Menthol E-CigarettesCDC Revises Number of Vaping-Linked Lung Illnesses to 380 in 36 StatesTrump Pushing for Nationwide Ban on Flavored E-CigarettesAre Hookahs Safer Than Cigarettes? Chemical Study Says No WayWould a Health Warning on Every Cigarette Help Smokers Quit?FDA Warns Juul About Illegal Marketing Claims and Pitch to YouthVaping-Linked Lung Illnesses Double, Vitamin E Acetate Leading SuspectHealth Officials Close in on Culprit in Vaping Lung Injury CasesAs Lung Injury Cases Rise, CDC Says 'Don't Vape'Jumps in Pot Use, Depression and Drinking Threaten Gains Against SmokingLots of Teens Are Breathing in Others' Vaping FumesVaping May Trigger Lung Damage Like That Seen in EmphysemaIn-Store Marketing Helps Get Kids VapingFirst Death Tied to Lung Injury From Vaping Reported in IllinoisCases of Lung Injury Tied to Vaping Keep RisingVaping Constricts Blood Vessels, Raising Heart, Lung ConcernsWhen Does Heart Health Return to Normal After Quitting Smoking?AHA News: Amid 'Epidemic' of School Vaping, a Search for SolutionsFDA Proposes Graphic Warning Labels on CigarettesE-Cig Use Triples Odds That Teens Will Smoke Pot: StudyRaising Legal Smoking Age to 21 WorksFDA Reports More Seizures Among VapersSmoking Creates Long-Lasting Risk for Clogged Leg ArteriesAHA News: Cigarette Smoke in Pregnancy May Impair Healing of Newborns' HeartsSmoking May Interfere With 'Embolization' Lung TreatmentNumber of American Smokers Who've Tried to Quit Has StalledMoney Motivates Smokers to Quit Long Term, Study FindsTough Rules on E-Cigs Might Push Folks Back to Smoking8 in 10 Americans Want Less Nicotine in Cigarettes: CDCFew U.S. Universities Are Smoke-FreeSocial Media a Big Driver of Teen Vaping Craze: StudyAHA News: Who's Helping Smokers Quit? Probably Not Their Heart DoctorYoung Female Smokers at Especially High Heart Risk'Secret Shopper' Study Shows How Easily Teens Can Buy E-CigsAnother Vaping Danger: E-Cigarette Explodes in Teen's FaceGlobal Efforts to Cut Smoking Show Mixed ResultsSheep Study Shows a Stuffy Side Effect of VapingAHA News: Vaping Ignites Legislative Trend to Raise Tobacco Sales Age to 21Cancer Patients Vaping in Growing NumbersVaping May Exact a Toll on Blood Vessel Health2 in 3 Adults Who Use E-Cigs Want to StopUnfiltered Cigarettes Are Most DeadlyVaping Habit Might Make You More Prone to FluNearly Half of Juul Twitter Followers Are Teens, Young Adults: StudyWhen E-Cig Makers Offer Promotional Items, More Teens Likely to VapeQuitting Smoking Helps Shield Women From Bladder Cancer: StudyE-Cigarettes Used in 5% of U.S. Homes With KidsFDA OKs Restricted Sales of 'Heat-Not-Burn' Tobacco DevicesVaping and Smoking May Signal Greater Motivation to QuitMany Smokers Switch to Vaping While Pregnant, But Safety Issues Remain
Questions and AnswersVideosLinksBook Reviews
Related Topics

Medical Disorders
Wellness and Personal Development

Vaping May Exact a Toll on Blood Vessel Health

HealthDay News
by By Dennis Thompson
HealthDay Reporter
Updated: May 28th 2019

new article illustration

TUESDAY, May 28, 2019 (HealthDay News) -- In yet another sign that electronic cigarettes are far from harmless, a new lab study suggests that vaping damages the cells that line the inside walls of blood vessels and could hasten heart trouble.

Lab-grown endothelial cells were more likely to die off or suffer from impaired function when exposed to e-cigarette vapor, the researchers reported.

If this same effect occurs in the human body, then e-cigarette users potentially could be at increased long-term risk of heart disease and stroke, said senior researcher Dr. Joseph Wu. He is director of the Stanford Cardiovascular Institute, in California.

"If you're a chronic e-cigarette [user], you're probably going to be prone to more vascular disease in the future," Wu said. "It doesn't have the carcinogens associated with smoking, but don't use e-cigarettes with the assumption that if I switch to e-cigarettes it will be good for my cardiovascular health."

Endothelial cells lining the interior surface of blood vessels play a critical role in heart health, the researchers explained.

These cells need to be flexible to help manage blood pressure, and if damaged they could attract more cholesterol plaques that contribute to narrowing of the arteries, and stroke, Wu said.

For the study, Wu and his colleagues grew endothelial cells from blood samples drawn from five smokers, five nonsmokers, two e-cigarette users and two people who use both e-cigarettes and tobacco cigarettes.

These endothelial cells then were exposed to six types of vapor from different e-liquids purchased online by the researchers.

Following exposure, the cells were more likely to die early and showed increased levels of DNA damage, the study authors said.

The cells also were less able to help form new blood vessels or participate in wound healing, the findings showed.

"The big picture is that, contrary to what people think, e-cigarettes are not perfectly safe," Wu said.

Exposure to cinnamon and menthol e-liquids proved particularly damaging to cells, the researchers reported. Caramel and vanilla flavors also disrupted the cells, but not as severely.

The findings were published online May 27 in the Journal of the American College of Cardiology.

Dr. Rose Marie Robertson is deputy chief medical officer of the American Heart Association. She said, "The remarkable thing was there were very strong effects, both in terms of the specific mechanisms they looked at and that the effects were not very different between cells from e-cigarette smokers and cigarette smokers."

Wu said that the researchers suspect that different components of e-cigarette vapor might harm blood vessel cells in different ways.

The vapor includes nicotine, flavorings and solvents, and all might contribute in different ways to cell death, oxidative stress on cells and inflammation, the study authors suggested.

Part of the problem is that e-cigarettes are using flavorings that have been approved by the U.S. Food and Drug Administration for ingestion, but not necessarily for inhalation, Robertson noted.

"Gradually, the evidence is accruing that shows these compounds have serious detrimental effects on cells," Robertson said.

Use of e-cigarettes has skyrocketed since their introduction a decade ago.

The FDA estimates that more than 3.5 million middle and high school students used e-cigarettes in 2018, even though sales to minors are prohibited. One in five high school students have tried e-cigarettes.

There's a lot of concern that these teens will wind up using e-cigarettes long-term, and that the damage done to their blood vessels will worsen over time, Wu and Robertson said.

"It's important for e-cigarette users to realize that these chemicals are circulating within their bodies and affecting their vascular health," Wu said.

More information

The U.S. Surgeon General has more about the health effects of e-cigarettes.




Facebook

Amazon Smile

To quit smoking, call Connecticut QuitLine at 1-800-QUIT-NOW.

Children and Adult services are available now with no wait time.  Please contact HBH Intake Department at 860-548-0101, option 2.

 


powered by centersite dot net